Infos zu Corona - Aktuelle Informationen zu SARS-CoV-2 : Was ist "Corona"?/use of term "corona"

Was ist "Corona"?/use of term "corona" » Rezeptoren/ receptors

Letzte Änderung: 13.06.2022 um 09:34 Uhr

Über die Rezeptoren ACE-2 und Neuropilin-1 scheint SARS-CoV-2 in die Zellen einzudringen.

Eine Videoanimation hierzu findet sich unter: https://coronavirus-annotation-2.sci.utah.edu/

Ein schematische Darstellung gibt es z.B. unter: https://www.bmj.com/content/bmj/371/bmj.m3862/F1.large.jpg

Weiterführende Links zum Artikel

★ Escape calculator for SARS-CoV-2 RBD (Hinzugefügt: 07.12.2021 um 07:10 Uhr)
https://jbloomlab.github.io/SARS2_RBD_Ab_escape_maps/escape-calc/
★ SARS-CoV-2 anatomy (Hinzugefügt: 05.03.2021 um 09:11 Uhr)
https://coronavirus-annotation-2.sci.utah.edu/
Tracking infectious entry routes of SARS-CoV-2 (Hinzugefügt: 13.06.2022 um 09:34 Uhr)
https://www.biorxiv.org/content/10.1101/2022.06.09.495472v1
SARS-CoV-2: Nahrungsmittelallergien könnten Ansteckungsrisiko senken (Hinzugefügt: 05.06.2022 um 15:28 Uhr)
https://www.aerzteblatt.de/nachrichten/134826/SARS-CoV-2-Nahrungsmittelallergien-koennten-Ansteckungsrisiko-senken
ACE2-independent infection of T lymphocytes by SARS-CoV-2 (Hinzugefügt: 03.04.2022 um 18:14 Uhr)
https://www.nature.com/articles/s41392-022-00919-x
Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease (Hinzugefügt: 08.03.2022 um 11:36 Uhr)
https://www.nature.com/articles/s41588-021-01006-7
Structures of the Omicron Spike trimer with ACE2 and an anti-Omicron antibody (Hinzugefügt: 19.02.2022 um 13:22 Uhr)
https://www.science.org/doi/10.1126/science.abn8863
Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement (Hinzugefügt: 17.02.2022 um 07:31 Uhr)
https://www.science.org/doi/10.1126/science.abn8652
Computational screening of potential drugs against COVID-19 disease: the Neuropilin-1 receptor as molecular target (Hinzugefügt: 17.02.2022 um 07:11 Uhr)
https://link.springer.com/article/10.1007/s13337-021-00751-x
Omicron favors neuropilin1 binding over ACE2: Increased infectivity and available drugs (Hinzugefügt: 17.02.2022 um 07:11 Uhr)
https://www.researchsquare.com/article/rs-1247982/v1
SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex (Hinzugefügt: 17.02.2022 um 06:36 Uhr)
https://www.science.org/doi/10.1126/science.abn7760
Omicron adopts a different strategy from Delta and other variants to adapt to host (Hinzugefügt: 14.02.2022 um 16:12 Uhr)
https://www.nature.com/articles/s41392-022-00903-5
Receptor binding and complex structures of human ACE2 to spike RBD from Omicron and Delta SARS-CoV-2 (Hinzugefügt: 11.01.2022 um 10:10 Uhr)
https://www.cell.com/cell/fulltext/S0092-8674(22)00001-0
The Omicron variant is highly resistant against antibody-mediated neutralization – implications for control of the COVID-19 pandemic (Hinzugefügt: 29.12.2021 um 17:53 Uhr)
https://www.cell.com/cell/fulltext/S0092-8674(21)01495-1
Compared with SARS-CoV2 wild type’s spike protein, the SARS-CoV2 omicron’s receptor binding motif has adopted a more SARS-CoV1 and/or bat/civet-like structure (Hinzugefügt: 23.12.2021 um 20:21 Uhr)
https://www.biorxiv.org/content/10.1101/2021.12.14.472585v1
SARS-COV-2 Omicron variant predicted to exhibit higher affinity to ACE-2 receptor and lower affinity to a larger range of neutralizing antibodies, using a rapid assessment platform (Hinzugefügt: 21.12.2021 um 12:30 Uhr)
https://www.biorxiv.org/content/10.1101/2021.12.16.472843v1
Coronavirus: Infektion in der Nase aufgeklärt (Hinzugefügt: 18.12.2021 um 15:00 Uhr)
https://www.scinexx.de/news/medizin/coronavirus-infektion-in-der-nase-aufgeklaert/
Mutations on RBD of SARS-CoV-2 Omicron variant result in stronger binding to human ACE2 receptor (Hinzugefügt: 18.12.2021 um 14:52 Uhr)
https://www.biorxiv.org/content/10.1101/2021.12.10.472102v2
SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection (Hinzugefügt: 13.12.2021 um 11:17 Uhr)
https://www.medrxiv.org/content/10.1101/2021.12.08.21267417v2
A sarbecovirus found in Russian bats uses human ACE2 (Hinzugefügt: 09.12.2021 um 17:56 Uhr)
https://www.biorxiv.org/content/10.1101/2021.12.05.471310v1
An antibody-escape calculator for mutations to the SARS-CoV-2 receptor-binding domain (Hinzugefügt: 09.12.2021 um 17:55 Uhr)
https://www.biorxiv.org/content/10.1101/2021.12.04.471236v1
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain (Hinzugefügt: 09.12.2021 um 17:51 Uhr)
https://www.science.org/doi/10.1126/science.abl6251
A Possible Role for Anti-idiotype Antibodies in SARS-CoV-2 Infection and Vaccination (Hinzugefügt: 28.11.2021 um 15:07 Uhr)
https://www.nejm.org/doi/full/10.1056/NEJMcibr2113694
Ovulatory upregulation of angiotensin-converting enzyme 2, a receptor for SARS-CoV-2, in dominant follicles of the human ovary (Hinzugefügt: 09.11.2021 um 16:05 Uhr)
https://pubmed.ncbi.nlm.nih.gov/34538460/
Identifying New COVID-19 Receptor Neuropilin-1 in Severe Alzheimer’s Disease Patients Group Brain Using Genome-Wide Association Study Approach (Hinzugefügt: 25.10.2021 um 07:29 Uhr)
https://www.frontiersin.org/articles/10.3389/fgene.2021.741175/full
Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2 (Hinzugefügt: 02.10.2021 um 18:37 Uhr)
https://www.pnas.org/content/118/42/e2106480118
High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape (Hinzugefügt: 22.09.2021 um 10:38 Uhr)
https://www.nature.com/articles/s41586-021-04005-0
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses (Hinzugefügt: 19.09.2021 um 14:39 Uhr)
https://www.nature.com/articles/s41467-021-25729-7
Characterization of SARS-CoV-2 and host entry factors distribution in a COVID-19 autopsy series (Hinzugefügt: 26.08.2021 um 04:29 Uhr)
https://www.nature.com/articles/s43856-021-00025-z
Proteases and variants: context matters for SARS-CoV-2 entry assays (Hinzugefügt: 24.08.2021 um 17:06 Uhr)
https://www.sciencedirect.com/science/article/pii/S1879625721000754
In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin (Hinzugefügt: 30.06.2021 um 15:25 Uhr)
https://www.nature.com/articles/s41598-021-92388-5
The SARS-CoV-2 RNA interactome (Hinzugefügt: 29.04.2021 um 07:40 Uhr)
https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00327-0
SARS-CoV-2 infection of the oral cavity and saliva (Hinzugefügt: 26.03.2021 um 20:51 Uhr)
https://www.nature.com/articles/s41591-021-01296-8.epdf?sharing_token=Goa--Y5eWW0LCTm4ySjCjtRgN0jAjWel9jnR3ZoTv0MqukDx6fkalF1K9TkeaYAdm7okeABRt96CYaeKH8LxBlinrqYSHhmWtwpVZpSIMj1N5AlBbCeFQGjPB3YEMidyXvy4OI9O4D-Zd1H85j5uXqb7Il8ogOp4OeejJQUL78A%3D
Covid-19 could be 'swallowed' into our bodies (Hinzugefügt: 26.03.2021 um 20:46 Uhr)
https://edition.cnn.com/2021/03/26/world/coronavirus-newsletter-intl-03-26-21/index.html
HOW UK, SOUTH AFRICA CORONAVIRUS VARIANTS ESCAPE IMMUNITY (Hinzugefügt: 25.03.2021 um 06:56 Uhr)
https://www.tacc.utexas.edu/-/how-uk-south-africa-coronavirus-variants-escape-immunity
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals (Hinzugefügt: 17.02.2021 um 03:04 Uhr)
https://www.pnas.org/content/118/9/e2026309118
Effect of ambient temperature on respiratory tract cells exposed to SARS-CoV-2 viral mimicking nanospheres—An experimental study (Hinzugefügt: 31.01.2021 um 10:19 Uhr)
https://avs.scitation.org/doi/10.1116/6.0000743
The SARS-CoV-2 Y453F mink variant displays a striking increase in ACE-2 affinity but does not challenge antibody neutralization (Hinzugefügt: 30.01.2021 um 11:31 Uhr)
https://www.biorxiv.org/content/10.1101/2021.01.29.428834v1
ACE2 and FURIN variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19 (Hinzugefügt: 29.01.2021 um 09:10 Uhr)
https://www.cell.com/heliyon/fulltext/S2405-8440(21)00238-3
Expert comment - new Brazilian variant of COVID-19 (Hinzugefügt: 17.01.2021 um 07:45 Uhr)
https://warwick.ac.uk/newsandevents/expertcomment/expert_comment_-_new_brazilian_variant_of_covid-191
Fatal neuroinvasion of SARS-CoV-2 in K18-hACE2 mice is partially dependent on hACE2 expression (Hinzugefügt: 16.01.2021 um 08:44 Uhr)
https://www.biorxiv.org/content/10.1101/2021.01.13.425144v1
The lethal triad: SARS-CoV-2 Spike, ACE2 and TMPRSS2. Mutations in host and pathogen may affect the course of pandemic. (Hinzugefügt: 15.01.2021 um 14:28 Uhr)
https://www.biorxiv.org/content/10.1101/2021.01.12.426365v1
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape (Hinzugefügt: 12.01.2021 um 20:28 Uhr)
https://science.sciencemag.org/content/early/2021/01/11/science.abe6230.full
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection (Hinzugefügt: 11.01.2021 um 19:06 Uhr)
https://www.nature.com/articles/s41588-020-00759-x
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2 (Hinzugefügt: 27.12.2020 um 11:33 Uhr)
https://www.pnas.org/content/117/45/28046
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2 (Hinzugefügt: 26.12.2020 um 14:59 Uhr)
https://science.sciencemag.org/content/370/6521/1208.full
Outsmarting SARS-CoV-2 by empowering a decoy ACE2 (Hinzugefügt: 26.12.2020 um 14:59 Uhr)
https://www.nature.com/articles/s41392-020-00370-w
CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells (Hinzugefügt: 15.12.2020 um 19:02 Uhr)
https://www.nature.com/articles/s41392-020-00426-x
Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2 (Hinzugefügt: 14.12.2020 um 07:16 Uhr)
https://www.pnas.org/content/early/2020/12/10/2021450118
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 (Hinzugefügt: 30.11.2020 um 19:59 Uhr)
https://www.nature.com/articles/s41593-020-00758-5
nanobodies that disrupt the interaction between Spike and ACE2 (Hinzugefügt: 06.11.2020 um 07:58 Uhr)
https://science.sciencemag.org/content/early/2020/11/04/science.abe3255.full
viral load is associated with increased disease severity (Hinzugefügt: 03.11.2020 um 08:56 Uhr)
https://www.nature.com/articles/s41467-020-19057-5
2 Rezeptoren (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.aerzteblatt.de/nachrichten/117616/Zweiter-Rezeptor-fuer-SARS-CoV-2-erklaert-breites-Symptomspektrum-von-COVID-19
„Hotspots“ für Coronaviren im menschlichen Körper (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.aerzteblatt.de/nachrichten/116286/Studie-findet-zahlreiche-Hotspots-fuer-Coronaviren-im-menschlichen-Koerper
timing of COVID-19 transmission (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.medrxiv.org/content/10.1101/2020.09.04.20188516v2
Variolation (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.nejm.org/doi/full/10.1056/NEJMp2026913
Virology, transmission, and pathogenesis (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.bmj.com/content/371/bmj.m3862
Neuropilin-1 (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://science.sciencemag.org/content/early/2020/10/19/science.abd2985.full
ACE Varianten (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456966/
2 Rezeptoren (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.scinexx.de/news/medizin/coronavirus-neuen-tueroeffner-in-die-zelle-entdeckt/
2 Rezeptoren (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.fr.de/wissen/die-zweite-eintrittspforte-fuer-das-virus-90076285.html
Neuropilin-1 (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://science.sciencemag.org/content/early/2020/10/19/science.abd2985.full
Neuropilin-1 (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://science.sciencemag.org/content/early/2020/10/19/science.abd3072.full
ACE-2 (Hinzugefügt: 01.11.2020 um 15:56 Uhr)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456966/

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